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immunotolerance 免疫耐受性 免疫耐受性 Tolerance \ Tol" er* ance\, n. [ L. tolerantia: cf. F. tol[' e] rance.] 1. The power or capacity of enduring; the act of enduring; endurance. [ 1913 Webster] Diogenes, one frosty morning, came into the market place, shaking, to show his tolerance. -- Bacon. [ 1913 Webster] 2. The endurance of the presence or actions of objectionable persons, or of the expression of offensive opinions; toleration. [ 1913 Webster] 3. ( Med.) The power possessed or acquired by some persons of bearing doses of medicine which in ordinary cases would prove injurious or fatal. [ 1913 Webster] 4. ( Forestry) Capability of growth in more or less shade. [ Webster 1913 Suppl.] 5. the allowed amount of variation from the standard or from exact conformity to the specified dimensions, weight, hardness, voltage etc., in various mechanical or electrical devices or operations; -- caklled also { allowance} specif.: ( Coinage) The amount which coins, either singly or in lots, are legally allowed to vary above or below the standard of weight or fineness. [ Webster 1913 Suppl. PJC] 6. ( Biochemistry) the capacity to resist the deleterious action of a chemical agent normally harmful to the organism; as, the acquired tolerance of bacteria to anitbiotics. [ PJC] 7. ( Immunology) the acquired inability to respond with an immune reaction to an antigen to which the organism normally responds; -- called also { immunotolerance}, { immunological tolerance}, or { immune tolerance}. Such tolerance may be induced by exposing an animal to the antigen at a very early stage of life, prior to maturation of the immune system, or, in adults, by exposing the animal to repeated low doses of a weak protein antigen ({ low- zone tolerance}), or to a large amount of an antigen ({ high- zone tolerance}). [ PJC] { Tolerance of the mint}. ( Coinage) Same as { Remedy of the mint}. See under { Remedy}. [ 1913 Webster]
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