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digitoxin    
毛地黄毒甙; 洋地黄毒甙

毛地黄毒□; 洋地黄毒□

digitoxin
n 1: digitalis preparation used to treat congestive heart
failure or cardiac arrhythmia

digitoxin \dig`i*tox"in\ (d[i^]j`[i^]*t[o^]k"s[i^]n), n. (Chem.)
A steroid glycoside, one of the cardiotonic chemical
substances which is extracted from the foxglove. It is a
white, crystalline substance ({C41H64O13}), and is a
3-substituted triglucoside of a steroid, related structurally
to digitalin and digoxin. It is used as a cardiotonic for
treatment of certain heart conditions, such as congestive
heart failure. Chemically it is

(3[beta],5[beta])-3-[(O-2,6-Dideoxy-[beta]-D-ribo-hexopyranosyl-(1[rarr]4)-O-2,6-dideoxy-[beta]-D-ribo-hexopyranosyl-(1[rarr]4)-2,
6-dideoxy-[beta]-D-ribo-hexopyranosyl)oxy]-14-hydroxy-card-20(22)-enolide.
The related compounds {digitalin} and {digoxin} are also
extracted from the foxglove ({Digitalis lanata} and
{Digitalis purpurea}). The class of steroid glycosides having
cardiotonic properties are refered to as the cardiac
glycoside group. --MI11
[PJC]


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  • Digitoxin - Wikipedia
    Digitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are longer-lasting
  • Digitoxin: Uses, Interactions, Mechanism of Action - DrugBank Online
    Digitoxin is a cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure
  • Digoxin Uses, Dosage Side Effects - Drugs. com
    Digoxin helps make the heart beat stronger and with a more regular rhythm Digoxin is used to treat heart failure Digoxin is also used to treat atrial fibrillation, a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart)
  • Digitoxin: Uses, Dosage, Side Effects, Food Interaction FAQ
    Learn about Digitoxin uses, dosage, side effects, food interactions, and more Get all the details about Digitoxin from MedicinesFAQ
  • Digitoxin - an overview | ScienceDirect Topics
    Digitoxin is a lipid-soluble cardiac glycoside that is used to treat congestive heart failure, arrhythmias, and heart failure It works by blocking the sodium-potassium ATPase in the plasma membrane, which leads to changes in intracellular sodium, calcium, and potassium levels
  • Digitoxin | pharmacology | Britannica
    Digoxin and digitoxin are commonly prescribed to increase the strength of heart contraction (These latter drugs evolved from digitalis, which was introduced in the 18th century as one of the first effective remedies for congestive heart failure, known at the time as “dropsy ”)
  • Digitoxin (Digitoxinum) - World Health Organization
    CAUTION: Digitoxin is extremely poisonous and should be handled with care Definition Digitoxin contains not less than 95 0% and not more than 105 0% of C41H64O13, calculated with reference to the dried substance Either tests A, B and D or tests B, C and D may be applied
  • Digitoxin - healthencyclopedia. org
    Chemically, digitoxin is a phytosteroid with the formula C41H64O13 It was first discovered and isolated from the leaves of the purple foxglove plant (Digitalis purpurea) in the late 18th century The primary medical use of digitoxin is in the treatment of heart failure
  • Digitoxin - Humanitas. net
    Digitoxin is used to treat heart problems such as heart failure, atrial fibrillation and paroxysmal atrial tachycardia What is Digitoxin? Digitoxin increases the force with which the heart works by increasing the strength of its contractions and reducing its rate
  • Digoxin Tablets: Uses Side Effects - Cleveland Clinic
    Take this medication by mouth with a glass of water Follow the directions on the prescription label Take your doses at regular intervals Do not take your medication more often than directed Talk to your care team about the use of this medication in children Special care may be needed





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