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lactam    
乳胺; 内酰胺

乳胺; 内□胺


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  • Lactam - Wikipedia
    A lactam is a cyclic amide, formally derived from an amino alkanoic acid through cyclization reactions The term is a portmanteau of the words lactone + amide Nomenclature
  • β-Lactams and β-Lactamase Inhibitors: An Overview - PMC
    β-Lactam antibiotics are bactericidal agents that interrupt bacterial cell-wall formation as a result of covalent binding to essential penicillin-binding proteins (PBPs), enzymes that are involved in the terminal steps of peptidoglycan cross-linking in both Gram-negative and Gram-positive bacteria
  • Beta-Lactam Antibiotics - StatPearls - NCBI Bookshelf
    Beta-lactam antibiotics are used in the management and treatment of bacterial infections This activity will highlight the mechanism of action, adverse event profile, and other key factors (e g , off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of an interprofessional
  • Overview of Beta-Lactams - Infectious Diseases - Merck Manual . . .
    Beta-lactamases are a diverse class of enzymes produced by bacteria that break open the beta-lactam ring, inactivating the beta-lactam antibiotic Some beta-lactamases are encoded on mobile genetic elements (eg, plasmids); others are encoded on chromosomes
  • Lactam - an overview | ScienceDirect Topics
    A lactam is a cyclic amide, which can be found in different forms: α-lactam (three-atom rings), β-lactam (four-atom rings), γ-lactam (five-atom rings), δ-lactam (six-atom rings), and ɛ-lactam (seven-atom rings) From: Green Approaches in Medicinal Chemistry for Sustainable Drug Design, 2020
  • What is Lactam? - BYJUS
    What is Lactam? A lactam is a cyclic amide, which is derived from an amino alkanoic acid The term is a portmanteau of the words acetone + amide Lactams form by the acid-catalysed rearrangement of oximes in the Beckmann rearrangement Lactams form from cyclic ketones and hydrazoic acid in the Schmidt reaction
  • β-Lactams and β-Lactamase Inhibitors: An Overview - PubMed
    β-Lactams are the most widely used class of antibiotics Since the discovery of benzylpenicillin in the 1920s, thousands of new penicillin derivatives and related β-lactam classes of cephalosporins, cephamycins, monobactams, and carbapenems have been discovered





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