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  • 细胞永生化技术 - 知乎 - 知乎专栏
    细胞永生化(Cell immortalization)是指体外培养的细胞经过自发的或受外界因素的影响从增殖衰老危机中逃离，从而具有增殖能力的过程。 正常组织来源的细胞在通常的体外培养条件下可分裂生长，但经过有限次数的传代后，就会停止增殖，发生衰老和死亡。
  • 永生化 - 维基百科，自由的百科全书
    癌细胞（图）就是一种发生永生化的细胞，具有突破海弗里克极限进行无限制分裂的能力 永生化（英語： Immortalized cells ）是指细胞取得可突破海弗里克极限、进行无限制分裂的过程。 永生化一般是端粒酶活化的结果。 在肿瘤发生过程中，永生化是正常细胞转变为癌细胞的标志之一 [1] 。
  • Cell Immortalization: In Vivo Molecular Bases and In Vitro Techniques . . .
    Cell immortalization is a useful tool in obtaining cell lines with an indefinite replicative potential as long as the conditions and nutrients necessary for their growth are present Through this pathway, the cell can exceed the Hayflick limit, evading the processes associated with replicative senescence and subsequent cellular apoptosis
  • IMMORTALIZE中文(简体)翻译：剑桥词典 - Cambridge Dictionary
    immortalize翻译：使不朽，使名垂千古。了解更多。
  • Cell Immortality: In Vitro Effective Techniques to Achieve and . . . - MDPI
    Cell immortalization proves to be a valuable technique for acquiring cell lines with unrestricted replicative capacity By following this approach, cells can surpass the Hayflick limit and evade the mechanisms linked to replicative senescence and eventual cell apoptosis
  • Cell Immortalization - an overview | ScienceDirect Topics
    Cell immortalization refers to the ability of certain cells, such as stem cells and cancer cells, to replicate indefinitely due to enhanced telomerase activity, thus avoiding the normal process of replicative cell senescence
  • immortalization - 百度百科
    immortalization，英语单词，主要用作为名词，意为不朽，不减；不灭。
  • Immortalization | definition of immortalization by . . . - Medical Dictionary
    immortalization A change in a eukaryotic cell line that confers the ability to go on dividing and reproducing indefinitely Immortalization implies the ability to continue to reform TELOMERES
  • Practical Use of Immortalized Cells in Medicine: Current . . . - MDPI
    Immortalization is the process of artificially overcoming the limit of cell divisions, which is carried out by changing the expression profile of the genes responsible for cell aging The first experiments on artificial immortalization of cells were conducted in the 1960s—using polyomaviruses [ 10 ] and chemical carcinogens [ 11
  • Mechanism of immortalization - PMC
    The generation of immortal cells lines, by the introduction of SV40 and human papillomavirus (HPV) sequences into cells, has provided invaluable tools to dissect the mechanisms of immortalization





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