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  • CD11c+ CD11b+ Dendritic Cells Play an Important Role in . . .
    Increased proportions of CD11c + CD11b + DCs and CD4 + CD25 + T cells in the CNS and spleen of tolerized mice To determine which DC subset is more abundant during induction of i v tolerance, we examined the relative populations of CD11c + CD11b + and CD11c + CD8α + DCs in the CNS and spleen after MOG 35–55-i v administration MOG 35–55
  • CD11c + B Cells Are Mainly Memory Cells, Precursors of . . .
    Finally, we show that patients with pemphigus, an autoimmune disease mediated by B cells, have a decreased frequency of CD11c + B cell after treatment, relative to baseline Our findings show that CD11c + B cells are mainly memory B cells prone to differentiate into antibody secreting cells that accumulate with age, independently of gender
  • CD11b + lung dendritic cells at different stages of . . . - Nature
    Dendritic cells (DC) in the lung that induce Th17 differentiation remain incompletely understood, in part because conventional CD11b+ DCs (cDC2) are heterogeneous Here, we report a population of
  • Conventional and Monocyte-Derived CD11b+ Dendritic Cells . . .
    Dendritic cells (DCs) are crucial for mounting allergic airway inflammation, but it is unclear which subset of DCs performs this task By using CD64 and MAR-1 staining, we reliably separated CD11b + monocyte-derived DCs (moDCs) from conventional DCs (cDCs) and studied antigen uptake, migration, and presentation assays of lung and lymph node (LN) DCs in response to inhaled house dust mite (HDM)
  • Dendritic Cell Accumulation in the Gut and Central Nervous . . .
    Whereas intraparenchymal CD11c + cells are likely microglial cells that are dispensable for the presentation of Ags to T cells, perivascular CD11c + cells are of hematopoietic origin and serve a nonredundant role for the stimulation of T cells in the CNS in steady-state and during inflammation (7–10)
  • Deep Phenotyping of CD11c+ B Cells in Systemic Autoimmunity . . .
    Thus, CD11c + B cells resided mainly within memory subsets and were enriched in CD27-IgD-, CD21-CD27-, and CD21-CD38-B cell phenotypes CD11c + B cells from all donor groups (SLE, pSS, and HD) showed enhanced CD69, Ki-67, CD45RO, CD45RA, and CD19 expression, whereas the membrane expression of CXCR5 and CD21 were diminished
  • Cheat Sheet to CD11c: Dendritic Cell Marker Explained
    CD11b is predominantly expressed on myeloid cells, and also on NK cells, mast cells, and a subset of T and B cells CD11c, on the other hand, is most abundant on dendritic cells Dr Tandon adds, “The distinction between CD11b and CD11c is crucial for researchers, as it can provide nuanced insights into cellular behavior and immune responses





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