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  • Crystalloid fluid therapy | Critical Care | Full Text - BioMed Central
    One of the key differences between 0 9 % saline and buffered balanced crystalloids is the presence of additional anions, such as lactate, acetate, malate and gluconate, which act as physiological buffers to generate bicarbonate
  • Are crystalloid-based fluid expansion strategies still relevant in the . . .
    Background Crystalloid-based fluid resuscitation has long been a cornerstone in the initial management of trauma-induced hemorrhagic shock However, its benefit is increasingly questioned as it is suspected to increase bleeding and worsen coagulopathy The emergence of alternative strategies like permissive hypotension and vasopressor use lead to a shift in early trauma care practices
  • Albumin versus crystalloid solutions in patients with the acute . . .
    Introduction In patients with acute respiratory distress syndrome (ARDS) fluid therapy might be necessary The aim of this systematic review and meta-analysis is to determine the effects of colloid therapy compared to crystalloids on mortality and oxygenation in adults with ARDS Methods Randomized controlled trials (RCTs) were identified through a systematic literature search of MEDLINE
  • Low-volume resuscitation with normal saline is associated with . . .
    Aggressively replacing severe blood loss with unbalanced crystalloids can result in hemodilution, changes in oxygen delivery, iatrogenic acidosis, and coagulopathy [1, 2] Recently, the concept of damage control resuscitation has emphasized decreased excessive crystalloid volumes and judicious administration of blood products [ 3 ]
  • Why physiology will continue to guide the choice between balanced . . .
    Background Crystalloids are the most frequently prescribed drugs in intensive care medicine and emergency medicine Thus, even small differences in outcome may have major implications, and therefore, the choice between balanced crystalloids versus normal saline continues to be debated We examined to what extent the currently accrued information size from completed and ongoing trials on the
  • Resuscitation fluid types in sepsis, surgical, and trauma patients: a . . .
    Background Crystalloids and different component colloids, used for volume resuscitation, are sometimes associated with various adverse effects Clinical trial findings for such fluid types in different patients’ conditions are conflicting Whether the mortality benefit of balanced crystalloid than saline can be inferred from sepsis to other patient group is uncertain, and adverse effect
  • Crystalloids vs. colloids: KO at the twelfth round? - Critical Care
    The authors were cautious to ensure that the intervention fluids of the two arms of the study had the expected composition by performing independent and random biochemical analyses In addition, the study targeted a more general ICU patient population, as compared to other recent clinical trials evaluating crystalloids versus colloids, such as 6S
  • Crystalloids versus colloids for goal-directed fluid therapy in major . . .
    Introduction Perioperative hypovolemia arises frequently and contributes to intestinal hypoperfusion and subsequent postoperative complications Goal-directed fluid therapy might reduce these complications The aim of this study was to compare the effects of goal-directed administration of crystalloids and colloids on the distribution of systemic, hepatosplanchnic, and microcirculatory (small
  • Crystalloid or colloid for resuscitation. Are we any the wiser?
    Crystalloid versus colloid in fluid resuscitation []A total of 26 trials were selected comparing a variety of colloids carried in a variety of crystalloid solvents and compared to a variety of crystalloids, including 3 5% gelatine in the crystalloid group in one study []
  • Rational or rationalized choices in fluid resuscitation?
    The war between colloids and crystalloids wages on In a large multinational survey of fluid prescribing practices in critically ill patients, we have a new and intriguing snapshot of global fluid resuscitation practices Colloids are more often used for impaired perfusion or low cardiac output, and the choice of colloid or crystalloid varies enormously between countries Why are some ICUs





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