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  • Nexletol shows CLEAR benefit in cardiovascular outcome trial
    New data for Esperion’s cholesterol lowering daily pill Nexletol, used when statins are not working in people at risk of a heart attack, could inject some momentum into the drug’s slow rollout
  • U. S. FDA Approves Broad New Labels for NEXLETOL® and NEXLIZET . . .
    U S FDA Approves Broad New Labels for NEXLETOL® and NEXLIZET® to Prevent Heart Attacks and Cardiovascular Procedures in Both Primary and Secondary Prevention Patients, Regardless of Statin Use
  • U. S. FDA Approves Broad New Labels for NEXLETOL® and NEXLIZET . . .
    ANN ARBOR, Mich , March 22, 2024 (GLOBE NEWSWIRE) -- Esperion (NASDAQ: ESPR) today announced that the United States Food and Drug Administration (FDA) has approved broad new label expansions for NEXLETOL ® (bempedoic acid) Tablets and NEXLIZET ® (bempedoic acid and ezetimibe) Tablets based on positive CLEAR Outcomes data that include indications for cardiovascular risk reduction and expanded
  • NEXLIZET® NEXLETOL® Other Outcomes Trial Information
    The most common adverse reactions in the cardiovascular outcomes trial for bempedoic acid, a component of NEXLIZET and NEXLETOL, at an incidence of ≥2% and 0 5% greater than placebo were hyperuricemia, renal impairment, anemia, elevated liver enzymes, muscle spasms, gout, and cholelithiasis
  • What Is NEXLETOL®? - Learn More About This Nonstatin Option
    The most common side effects of NEXLETOL in people with heart problems include: Kidney problems, anemia, increased liver enzymes, muscle spasms, and gallstones NEXLETOL can cause serious side effects, including: Increased levels of uric acid in the blood, which can lead to gout, a painful joint condition
  • Impact of SGLT2 Inhibitors on Cardiovascular Risk Scores . . .
    Background: Cardiovascular disease (CVD) is a leading cause of mortality in Type 2 diabetes mellitus (T2DM) Sodium-glucose co-transporter 2 (SGLT2) inhibitors are known to provide cardioprotective effects, but their influence on validated cardiovascular risk models remains underexplored This study assessed the impact of SGLT2 inhibitors on cardiovascular risk scores, metabolic parameters
  • Therapeutic Value of SGLT2 Inhibitors in the Management of . . .
    SGLT2 inhibitors have transformed the treatment of cardiovascular disease, providing substantial therapeutic promise for a wide range of patients They are anticipated to become more and more important in the prevention and management of cardiovascular disease
  • SGLT2 Inhibitors Shown to Improve Outcomes in Amyloid Heart . . .
    SGLT2 inhibitors were associated with significantly lower 12-month all-cause mortality and hospitalization in patients with heart failure due to ATTR, a study shows
  • FDA Approves Broad New Labels for NEXLETOL® and NEXLIZET® to . . .
    Esperion announced that the FDA approved broad new label expansions for NEXLETOL® (bempedoic acid) Tablets and NEXLIZET® (bempedoic acid and ezetimibe) Tablets based on positive CLEAR Outcomes data that include indications for cardiovascular risk reduction and expanded LDL-C lowering in both primary and secondary prevention patients
  • U. S. FDA Approves Broad New Labels for NEXLETOL® and NEXLIZET . . .
    The U S approvals of NEXLIZET and NEXLETOL for cardiovascular risk reduction and LDL-C lowering were based on data generated from the CLEAR Outcomes trial, which was published in the New England Journal of Medicine in March 2023, assessing the effect of NEXLETOL on cardiovascular outcomes in nearly 14,000 patients with, or at high risk, of





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