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  • Is there a difference in testosterone levels and its . . .
    Male BRCA mutation carriers are at risk for an early onset aggressive prostate cancer No data exist on the association of testosterone levels among these patients We aimed to analyze testosterone and associated hormonal levels among male BRCA carriers and non-carriers
  • Hormone Replacement Therapy in Carriers of the BRCA1 Mutation
    Can hormone replacement therapy be used in women with BRCA1 mutations? Women’s health specialist Pelin Batur, MD, summarizes current literature evaluating the potential risks and benefits for this patient population
  • What Men Need to Know About BRCA and Other Gene Mutations
    Prostate cancer in men is probably the most significant cancer risk of having a BRCA gene mutation, more so than breast cancer Are there racial or ethnic differences in both the prevalence of BRCA mutations and the impact of having a mutation? Yes, and all of genetics is ancestry
  • Hormone replacement therapy in BRCA mutation carriers and . . .
    BRCA mutation carriers have an increased risk of developing breast or ovarian cancer Risk-reducing bilateral salpingo-oophorectomy (RRBSO) is associated with a decrease in risk for tubal and ovarian cancer Hormone replacement therapy (HRT) may increase breast, ovarian, and endometrial cancer risk in the general population
  • HRT for those with high inherited risk of cancer
    Taking estrogen can help but it is often replacement testosterone that significantly improves these particular symptoms Testosterone is usually given as a gel or cream that you rub into your skin It can sometimes take a few months for the full effects to work in your body
  • BRCA1 and BRCA2 in Men - Basser
    Man can carry BRCA1 or BRCA2 gene mutations and can be at increased risk for certain cancers While cancer risks in male BRCA mutation carriers are not as dramatically elevated as those of female BRCA mutation carriers, cancer risk management and early detection are crucial
  • Serum testosterone and prostate cancer in men with germline
    Accumulating evidence has shown that BRCA2 pathogenic variants (PVs) carriers are at higher risk of developing prostate cancer (PCa), estimated to be 2 5–8 6 fold, and that their disease progression is especially accelerated 1 , 2 , 3 , 4 Despite representing a small fraction of PCa cases (0 45%–1% and 1 2% for BRCA1 and BRCA2





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