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  • P-Glycoprotein Monoclonal Antibody (UIC2) - Thermo Fisher Scientific
    Mouse anti Human CD243, clone UIC2 recognizes an extracellular conformational epitope of CD243, also known as MDR1 (multi-drug resistance protein 1) and Pgp (P-glycoprotein), a multi pass transmembrane protein and member of the ABC transporter (ATP-binding cassette) family, containing two ABC transporter type 1 domains and two ABC transporter
  • Anti-MDR1 Antibody, clone UIC2, azide free - MilliporeSigma
    UIC2 is a mouse monoclonal antibody directed against the extracellular conformational epitope of P-glycoprotein (Pgp) This antibody can be used in flow cytometry, immunofluorescence microscopy and immunohistochemistry in frozen and paraffin sections to detect Pgp expression on the membrane of MDR1 positive cells
  • Anti-P Glycoprotein PE antibody [UIC2] (ab93590) IgG2a - Abcam
    Mouse Monoclonal P Glycoprotein antibody - conjugated to PE Suitable for Flow Cyt and reacts with Human samples Cited in 11 publications Flow Cytometry - PE Anti-P Glycoprotein antibody [UIC2] (ab93590) Staining of the human 8226 S (blue histogram) and human 8226 DOX40 (purple histogram) cell lines with PE Mouse IgG2a, K Isotype Control
  • The Strong In Vivo Anti-Tumor Effect of the UIC2 Monoclonal Antibody Is . . .
    P-glycoprotein (Pgp) extrudes a large variety of chemotherapeutic drugs from the cells, causing multidrug resistance (MDR) The UIC2 monoclonal antibody recognizes human Pgp and inhibits its drug transport activity However, this inhibition is partial, since UIC2 binds only to 10–40% of cell surface Pgps, while the rest becomes accessible to this antibody only in the presence of certain
  • PE Mouse Anti-Human P-glycoprotein (CD243) - BD Biosciences
    P-glycoprotein is known to impart drug resistance to cells by pumping many anti-cancer drugs out of the cytoplasm 17F9 antibody is able to partially block the binding of UIC2 antibody (another MDR-specific monoclonal antibody) Flow cytometric profile of P-glycoprotein (CD243) expression on PMG-Y cell line PMG-Y cells were
  • Monoclonal antibodies specific for P-glycoprotein - Nature
    Monoclonal antibodies for P-gp E Okochi et al 1120 kemic MDR cells 12 C219 recognizes a cytoplasmic sequence used to eliminate the unspecific binding of antibody to Fc of six residues away from
  • Anti-P Glycoprotein Antibody [UIC2] (PE) (A85649)
    Mouse monoclonal [UIC2] antibody to P Glycoprotein (PE) (A85649) Validated for Flow Cytometry and reacts with Human samples 1 scientific validation image +1 (314) 370-6046 or
  • Complete Inhibition of P-glycoprotein by Simultaneous Treatment with a . . .
    Several monoclonal antibodies (mAb) recognizing discontinuous extracellular epitopes of Pgp have been developed A few of them (e g , MRK16, MRK17, MC57, HYB-241, and UIC2 in particular) seem to partially inhibit Pgp-mediated drug export in vitro or in vivo (Chaudhary et al , 1992; Mechetner and Roninson, 1992; Rittmann-Grauer et al , 1992; Jachez et al , 1994), and it was also found that
  • Anti-P Glycoprotein antibody [UIC2] (GTX42220) | GeneTex
    Mouse Monoclonal P Glycoprotein antibody [UIC2] (GTX42220) Validated in ICC IF, IHC-P, IHC-Fr, FCM, IP Tested in Human
  • Efficient Inhibition of P-Glycoprotein-Mediated Multidrug Resistance . . .
    therapy We have developed a mouse monoclonal antibody, UIC2, that recognizes an extracellular epitope of human Pgp UIC2 inhibited the efflux of Pgp substrates from MDR cells and significantly increased the cytotoxicity of Pgp-transported drugs, under the conditions where no effect was detectable with other anti-Pgp antibodies
  • P-Glycoprotein Monoclonal Antibody (UIC2) - Thermo Fisher Scientific
    Invitrogen Anti-P-Glycoprotein Monoclonal (UIC2), Catalog # MA5-44031 Tested in Immunohistochemistry (Frozen) (IHC (F)), Immunohistochemistry (Paraffin) (IHC (P)), Flow Cytometry (Flow) and Immunoprecipitation (IP) applications This antibody reacts with Human samples Supplied as 100 µg purified antibody (1 mg mL)
  • Anti-MDR1 Antibody, conformational extracellular epitope, clone UIC2 . . .
    UIC2 is a mouse monoclonal antibody directed against the extracellular conformational epitope of P-glycoprotein (Pgp) This antibody can be used in flow cytometry, immunofluorescence microscopy and immunohistochemistry in frozen and paraffin sections to detect Pgp expression on the membrane of MDR1 positive cells





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